قسم الطب الوقائي

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حول قسم الطب الوقائي

أ‌. علم سلوكيات ورعاية الحيوان:يهدف هذا المقرر إلى التعريف بأسس تربية ومعاملة الحيوانات ورعايتها مع تغطية كاملة لقواعد الرعاية الصحية والسلوكية المتعلقة بالفرد والقطيع.ب‌.علم الوراثة والأنسال:يهدف علم الوراثة والأنسال إلى التعريف بالقواعد الأساسية لعلم الوراثة وقوانينها للإستفادة منها في الرفع من الإنتاجية.ج‌. علم صحة وإدارة القطعان:يهدف هذا المقرر إلى التعريف بالبرامج المختلفة المتعلقة بصحة وإدارة القطعان الحيوانية.د‌. علم الوبائيات:يدرس الطالب في هذا المقرر العوامل المؤثرة على صحة القطعان الحيوانية ومسببات الأمراض وطرق انتشارها  وتركيب القطعان الحيوانية وأشكال حدوث الأمراض في القطعان الحيوانية وطرق التشخيص الوبائي إضافة إلى طرق قياس حدوث المرض في القطعان الحيوانية بهدف الوصول إلى فرضية تحديد مسببات المرض لكي يتم اختبار هذه الفرضية من خلال علم الوبائيات التحليلي والذي يتم من خلاله استخدام الدراسات التجريبية أو دراسات الملاحظة لتحديد العلاقة بين التعرض للمسبب المرضي وحدوث المرض، وفى هذا العلم يدرس الطالب المسوحات الوبائية والترصد الوبائي وعلم الوبائيات المصلي وهي المعلومات التي تستخدم من أجل التحكم في الوباء في حال حدوثه.هـ. علم الأمراض المشتركة:يدرس الطالب في هذا المقرر تصنيف الأمراض المشتركة وأهم أنواعها مع التركيز على وبائيتها وطرق مقاومتها على المستوى الوطني والعالمي مع التعريف بالمنظمات الدولية المختصة والأمراض الواجب التبليغ عنها حال اكتشافها محليا ودوليا.

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Genetic variants within the second intron of the KCNQ1 gene affect CTCF binding and confer a risk of Beckwith–Wiedemann syndrome upon maternal transmission.

Background Disruption of 11p15 imprinting results in two fetal growth disorders with opposite phenotypes: the Beckwith–Wiedemann (BWS; MIM 130650) and the Silver–Russell (SRS; MIM 180860) syndromes. DNA methylation defects account for 60% of BWS and SRS cases and, in most cases, occur without any identified mutation in a cis-acting regulatory sequence or a trans-acting factor. Methods We investigated whether 11p15 cis-acting sequence variants account for primary DNA methylation defects in patients with SRS and BWS with loss of DNA methylation at ICR1 and ICR2, respectively. Results We identified a 4.5 kb haplotype that, upon maternal transmission, is associated with a risk of ICR2 loss of DNA methylation in patients with BWS. This novel region is located within the second intron of the KCNQ1 gene, 170 kb upstream of the ICR2 imprinting centre and encompasses two CTCF binding sites. We showed that, within the 4.5 kb region, two SNPs (rs11823023 and rs179436) affect CTCF occupancy at DNA motifs flanking the CTCF 20 bp core motif. Conclusions This study shows that genetic variants confer a risk of DNA methylation defect with a parent-of-origin effect and highlights the crucial role of CTCF for the regulation of genomic imprinting of the CDKN1C/KCNQ1 domain. arabic 26 English 132
Julie Demars, Mansur Ennuri Moftah Shmela, Abdul Waheed Khan , Kai Syin Lee, Salah Azzi, Patrice Dehais, Irène Netchine, Sylvie Rossignol, Yves Le Bouc, Assam El-Osta, Christine Gicquel(7-2014)
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Blood profile in normal one humped dromedary (Camelus dromedarius) camel breeds in Libya. Part 3: Effect of sex variation on biochemical and haematological blood profile

As little is known about the blood profile of camels in Libya, this article is the third of a 4-part series describing the biochemical and haematological blood profile in Libyan camels. In part 1 of these manuscripts, the overall blood biochemical and haematological mean values of camels in Libya were determined, parts 2-4 evaluate the effects of breed, gender and age respectively on these values. Blood samples were collected from 24 male and 42 female apparently healthy camels and the levels of enzymes, metabolites, electrolytes and haematological indices were measured. The blood of the male camels showed higher values of aspartate aminotransferase (AST), Lactate dehydrogenase (LDH), Amylase (AMS), total proteins, globulin and Phosphorus (Ph), than the female camels which showed higher values of glucose, Albumin/Globulin (A/G) ratio, urea, Iron (Fe), Calcium (Ca), Packed Cell volume (PCV), Haemoglobin (Hb), erythrocyte osmotic fragility, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), neutrophil and monocyte numbers. This study shows significant sex differences between male and female Libyan camels in many haematological and biochemical analytes. arabic 28 English 141
Anwar Mustafa Abdalhadi Abdalmula, Fathia mahmoud Mohammad Ashour, Mansur Ennuri Moftah Shmela, Fahima A Alnagar, Ismail M Abograra, Amal Omar Elarif Buker(1-2019)
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Health adverse effects of formaldehyde exposure to students and staff in gross anatomy

Formaldehyde is an anxious gas used as a tissue preservative of cadavers in anatomy halls. Therefore, laboratory staff and students are at high risk of different clinical complications due to the continuous exposure to formaldehyde. The present questionnaire-based study evaluates the effects of formaldehyde exposure on veterinary students and staff in the anatomy gross dissection laboratory, University of Tripoli, Libya. A total of 104 students and 6 anatomy staff members completed a questionnaire of 24 questions related to the clinical symptoms observed after formaldehyde exposure and the answers were assessed using a six point (0-5) scale. Students had a high prevalence of nasal itching 78(75%), eyes burning 78(75%), excessive lacrimation 76(73%), eyes redness 60(58%), headache 64(62%) and respiratory distress 61(59%). Smoking and wearing glasses or gloves worsened many symptoms while wearing masks minimized other symptoms and male students were more affected than females. All anatomy staff members (100%) reported nasal itching, burning and congestion, eyes burning and redness, excessive lacrimation, cough and respiratory distress and less than that (83%) suffered from mouth dryness, headache, temporary loss of their ability to recognize the smell of formaldehyde and needed a physician assistance after the exposure to formaldehyde. The repeated exposure to formaldehyde in gross anatomy dissection has harmful effects on both students and staff member and finding alternative preservation methods, such as freezing, would be safer than using the formaldehyde. arabic 12 English 74
Fahima A Alnagar, Mansur Ennuri Moftah Shmela, , Abdulrhman Mohamed Salah Alrtib, , Fathia mahmoud Mohammad Ashour, Amal Omar Elarif Buker, Anwar Mustafa Abdalhadi Abdalmula(10-2015)
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