كلية الطب البشري

المزيد ...

حول كلية الطب البشري

لقد تم تأسيس كلية الطب البشري في سنة 1973م، بمدينة طرابلس لتقوم بدورها المنوط بها والمتمثل في تخريج الكوادر الطبية المؤهلة، وفي سنة 1980م تم تخريج أول دفعة منها.

تعد كلية الطب البشري من أكبر كليات الجامعة وصرحاً من صروح المعرفة، بحيث أسهمت هذه الكلية خلال العقود الأربعة الماضية في إعداد وتخريج أطباء مؤهلين كان لهم الفضل بعد الله تعالى في إنجاح العمل الطبي من خلال المستشفيات المنتشرة في ربوع الوطن الحبيب لتقديم أفضل الخدمات الصحية، تضم كلية الطب البشري حالياً أكثر من 493 عضو هيئة تدريس جُلهم من العناصر الوطنية الذين كانوا من أوائل الدفعات في هذه الكلية والذين ساهموا في تقديم الخدمات الصحية اللازمة في المستشفيات والعيادات والمستوصفات.

قد تم إيفاد العديد من خريجي هذه الكلية لاستكمال دراستهم في الخارج والذين أثبتوا جدارتهم في التحصيل العلمي والسريري بشهادة العديد من الجامعات العالمية، هذا وفي الوقت الذي تسعي فيه الكلية لتفعيل برنامج الدراسات العليا في مختلف التخصصات فإنها تعمل علي تطوير مفردات مناهجها وطرق التدريس المواكبة لمتطلبات الجودة العالمية.

حقائق حول كلية الطب البشري

نفتخر بما نقدمه للمجتمع والعالم

79

المنشورات العلمية

237

هيئة التدريس

7385

الطلبة

0

الخريجون

من يعمل بـكلية الطب البشري

يوجد بـكلية الطب البشري أكثر من 237 عضو هيئة تدريس

staff photo

أ. فتحية احميدة صالح بن صالح

منشورات مختارة

بعض المنشورات التي تم نشرها في كلية الطب البشري

Prevalence of Vitamin D Deficiency in Pregnant Diabetic Patients in Western Libya

Despite the relative abundance of sunny weather, surprisingly, there is increasing evidence that vitamin D deficiency is extremely prevalent in females of reproductive age in Middle East countries. There is also increasing interest in the non-classical roles of vitamin in health and disease including its relation to incidence of gestational diabetes, its impact on glycaemic control in diabetes mellitus, and its association with some complications of pregnancy like preeclampsia. The objective of this study was to estimate the prevalence of Vitamin D deficiency in pregnant diabetic patients in west Libya and analyse potential links to socioeconomic and cultural factors. This is a cross sectional observational study. Random plasma was collected form expected mothers attending the Antenatal Diabetes Clinic at Tripoli’s Main Maternity Hospital. Demographics and socioeconomic and cultural factors were recorded at the same time. Samples were analysed for vitamin D level and biochemical screening panel. Vitamin D level was obtained from 160 patients (mean age 35 years). Over all 95 % of the study population had vitamin D levels below normal (defined as vitamin D level of < 20 ng/mL). Results were subcategorised into severe deficiency ( 30 ng/ml, only 1.3%, 2 patients). All patients were taking daily vitamin D Supplements at a dose of 400 IU as per hospital policy. Vitamin D deficiency is extremely prevalent in pregnant diabetic patients in Libya. There is no clear association with socioeconomic risk factors like employment, type of accommodation or geographic distribution. However, most of the study population had life style characterized by minimal exposure to direct sun arabic 11 English 70
G Murad, A Bashein(1-2019)
Publisher's website

Fertility and Reproductive Outcome in Mice Following Trichloroethane (TCE) Exposure

Exposure to trichloroethane (TCE), an industrial solvent, has been shown to be negatively associated with reproductive performance. The present study was performed to assess the effects of TCE exposure on the reproductive performance and outcome in mice during a critical developmental window of later reproductive life. A group of female mice were injected intraperitoneally twice weekly for three weeks with TCE (100 and 400 µg/kg). Mice were followed up for signs of toxicity and death. Changes in uterine tissues have also been investigated by histopathology. The results showed that TCE exposure has reduced the number of F0 fertile females comparing to controls. Moreover, TCE exposure resulted in a decreased pups number and changed sex ratio in the litter of F0 TCE­treated dams. Histopathological examination revealed a TCE­induced uterine toxicity appeared as a severe endometrial hyperplasia with squamous cell metaplasia and adenomyosis. These results indicate that TCE exposure during a critical reproductive developmental window could affect the fertility and interfere with the reproductive outcome in mice.
Mohamed A. Al-Griw, Seham A. Azreg, Emad M. Bennour, Salem A. El-Mahgiubi, Ali R. Al-Attar, Naser M. Salama, Abdul Hakim Elnfati(10-2015)
Publisher's website

CYP1A1 Genetic Variations and Lung Cancer Risk in a Population of Libyan Males

Alterations in genes encoding the xenobiotic-metabolizing enzymes contribute to the variability in susceptibility to various cancers. In this study, we assessed the possible association between the CYP1A1 variants and lung cancer (LC) risk in a population of Libyan males. For this study, we selected 20 unrelated healthy controls and 32 patients with LC. DNA samples from the controls and patients were screened by DNA-PCR and direct DNA sequence analysis to search for genetic sequence variations in CYP1A1 gene (exon 7 and 3’ non-coding region). CYP1A1 mutations were identified in 11.5 % adult subjects and cases analyzed, and all were males. Overall, 11 CYP1A1 mutations were documented in this study implicating exon 7 and 3’ non-coding region. Nonsense, missense, and frame-shift mutations accounted for, respectively, 27.3 %, 63.6 % and 9.1 % of all CYP1A1 mutations. Three missense mutations namely CYP1A1*2B/m2 (rs1048943), CYP1A1*4/m4 (rs1799814), and CYP1A1*2A/m1 (rs4646903) have already been reported. The remaining mutations have not been described previously. We observed two apparently heterozygous carriers of mutation CYP1A1*2B/m2 (CYP1A1 4889A/G [642Ile/Val] genotype) in control group. We also observed two heterozygotic genotypes one containing mutation m4 (CYP1A1 4887C/A [461Thr/Asp]) and another containing mutation m1 (6235T/C) in cancer group. The mutations m2, m4, and m1 accounted for, respectively, 18.2 %, 9.1 % and 9.1 % of all CYP1A1 mutations. Comparing the clinical features showed that PLT and WBC counts were lower in CYP1A1 mutant than in CYP1A1 wild type, but they have not reached statistical significant (P > 0.05). The average age of CYP1A1 mutant was lower than in CYP1A1 wild type. Overall, these findings suggest that genetic alterations in the metabolic gene CYP1A1 are too rare to be of clinical relevance in this study, implying different pathways for the LC risk with respect to CYP1A1 polymorphisms as a risk factor for LC at least in this study.
Najah A. Fares, Othman A. El-Ansari, Mohamed A. Al-Griw(4-2017)
Publisher's website